Abstract: Pre-eclampsia is an idiopathic disease during pregnancy, affecting 2%-8% of pregnancies, and remains the leading cause of maternal and perinatal morbidity and mortality worldwide, which can lead to hypertension and multiple organ dysfunction. So far, no effective treatment measure but termination of pregnancy. Although maternal clinical indicators and vascular lesions may gradually returns to normal after childbirth, but the transient, temporary acute gestational complication leads to vascular endothelial injury and inflammation immune overactivation. There is growing evidence that the maternal effects of pre-eclampsia are not limited to pregnancy and puerperium. Women with pre-eclampsia have an increased risk of cardiovascular disease, kidney disease, metabolic syndrome and diabetes, hypothyroidism and thromboembolism, as well as cognitive impairment and malignancies in many years. This paper reviews the impact of pre-eclampsia on long-term maternal disease and analyzes whether pre-eclampsia can lead to an increased risk of these diseases, so as to contribute to the establishment of a reasonable and comprehensive postpartum management program for women with a history of pre-eclampsia, timely health guidance and intervention, and the improvement of long-term health.

Key words: Pre-eclampsia;, Pregnancy complications;, Long-term complications;, Pregnant women;, Cardiovascular diseases