Abstract:

A case of advanced ovarian cancer with inguinal lymph node metastasis was reported. The patient presented with abdominal distension for 3 months and self-palpated abdominal mass for 2 months. Imaging examinations revealed a large pelvic masses and pelvic effusion, as well as multiple enlarged lymph nodes in the left inguinal region, which were highly suspected to be metastasis. Subsequently, cytoreductive surgery for ovarian malignant was performed. Postoperative pathological biopsy indicated high-grade serous carcinoma of left ovary, stage ⅣB, with left inguinal lymph node metastasis. Intravenous chemotherapy was performed after surgery. In the first cycle, paclitaxel and carboplatin were used for chemotherapy. In the second cycle, bevacizumab was added to the original chemotherapy regimen for targeted therapy. After 6 cycles of chemotherapy and 17 cycles of targeted therapy, maintenance therapy with niraparib has been continued to date. There have been no obvious adverse reactions, and no tumor recurrence or metastasis has been observed.

Key words: Ovarian neoplasms, Lymphatic metastasis, Groin, Antineoplastic combined chemotherapy protocols, Case reports