Abstract: Objective: To evaluate the clinical effect in patients with complete septum uterus, duplicated cervix and vaginal septum after hysteroscopic electroresection combined with laparoscopy. Methods：We retrospectively analyzed the clinical data of 27 patients with complete septum uterus, duplicated cervix and vaginal septum undergoing hysteroscopic resection combined with laparoscopy from 2012 to 2013 in Gynecological Minimal Invasive Center in Beijing Obstetrics and Gynecology Hospital Affiliated to Capital Medical University. There are primary infertility 7, nature abortion 10, missed abortion 4, abnormal childbearing history 7. Results: The success rate of surgery was 100% without intra- or post-operative complications. The duration of post-operative follow-up ranged from 30 to 53 months, with an average of （41.56±6.33） months. There are full-term delivery 18 cases, premature delivery 1, nature abortion 2, inferlity 3, induced labor due to fetal anomaly 1, lost 1, have no birth plan 3. The pregnancy rate of patients with complete uterine septum increased from 52.17% （11/23, pre-operation） to 86.96% （20/23, post-operation, χ2=6.33, P=0.01）. The full-term live birth rates increased from 0（0/23, pre-operation） to 82.61% （19/23, post-operation, P=0.000）. The spontaneous abortion rates decreased from 47.83% (11/23, pre-operation） to 8.70% （2/23, post-operation, χ2=6.86, P=0.008）. Conclusions: Hysteroscopic resection of uterine septum is safe and effective. For patients with complete uterine septum, hysteroscopic resection of septum combined with laparoscopy can increase the full-term live birth rate, decrease spontaneous abortion rate, and improve patients' reproductive prognosis.

Key words: Hysteroscopes, Laparoscopes, Mullerian ducts, Vaginal septum and duplicated cervix, Complete septum uterus