Abstract: Among abnormal uterine structure diseases, the prevalence of adenomyosis is higher in childbearing age women. With the improvement of medical image technique and treatment, more and more findings show that adenomyosis may affect the fertility of childbearing age women. Currently, the mechanism of adenomyosis resulting in infertility is unclear, abnormal receptivity of the endometrial, abnormal structures of the uterine junctional zone, and dysfunction of immune in uterine can cause the infertility in these patients. The main treatment options are drug therapy, assisted reproductive technology (ART), and surgical resection of adenomyosis for women with fertility inspiration. The gonadotropin-releasing hormone analogs has a positive effect on reproduction function, while ART can improve the pregnancy outcome in infertile women with adenomyosis, both have important value in the treatment of infertility in women with adenomyosis. This article reviews the mechanisms, pregnancy outcomes and therapeutic strategies of infertility in women with adenomyosis to investigate the associations between adenomyosis and infertility.

Key words: Endometriosis, Infertility, female, Reproductive technology, assisted, Pregnancy, Gonadotropin-releasing hormone