Abstract: Gut microbiota is a complex and huge community of microorganism species living in the digestive tracts. Gut microbiota is capable of producing a diverse range of compounds that significantly affect host physiology, energy homeostasis, inflammatory process and immune function, and it plays an important role in maintaining body health. In recent years, the structure and physiological functions of gut microbiota, changes in gut microbiota during pregnancy, and the correlation between gut microbiota and pregnancy diseases have become hot topics. Although the etiology and pathogenesis of pre-eclampsia are still unclear, most of the findings are related to vascular factors, immune imbalance, and systemic inflammatory response factors. It has been found that gut microbiota may play a role in the occurrence and development of pre-eclampsia through vascular factors, immune response, inflammatory response. Adjusting the diet structure and supplementing the microecological regulator can regulate the intestinal flora disorder, thereby preventing or alleviating pre-eclampsia. It provides new targets and ideas for exploring the prevention and treatment of pre-eclampsia.

Key words: Pre-eclampsia, Intestines, Microbiome, Therapy