Journal of International Obstetrics and Gynecology ›› 2019, Vol. 46 ›› Issue (2): 220-224.

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Progress in Clinical Research of Endometrial Polyps with Infertility

WANG Yang-xin,LI Meng,LU Mei-song   

  1. Department of Obstetrics and Gynecology,The First Affiliated Hospital of Harbin Medical university,Harbin 150001,China
  • Received:2018-11-16 Revised:2018-12-21 Published:2019-04-15 Online:2019-04-15

Abstract: Endometrial polyps (EP) are a common cause of reduced fertility in women and an independent factor affecting embryo implantation via artificial assisted techniques. Excessive exposure to estrogen, chronic inflammatory stimuli, or cell proliferation/apoptosis imbalance may be associated with its pathogenesis. The mechanism by which EP causes infertility is still unclear, and may be related to the formation of mechanical interference in the implantation of embryos in the uterine cavity and the alteration of the microenvironment of the endometrium. The probability of malignancy is very low. In most cases, EP with diameter <1 cm has the possibility of self-resolving, and you can choose expectant treatment. For infertile women, the choice of transcervical resection of polyp (TCRP) can improve the natural pregnancy rate and assisted reproductive success rate of infertile patients. There is currently no specific treatment regimen recommended for EP patients newly diagnosed during controlled ovarian hyperstimulation (COH). Related clinical studies have shown that frozen-thawed embryo transfer (FET) after TCRP can improve clinical pregnancy rate.

Key words: Endometrium, Polyps, Infertility, female, Therapy, Pregnancy rate