Abstract: Uterine Serous Carcinoma [USC, also known as uterine papillary serous carcinoma (UPSC)] is a special pathological type of type Ⅱ endometrial cancer, with the characteristics of strong invasiveness, high postoperative recurrence rate, prone to distant metastasis, poor prognosis and so on. Because of its low incidence and lack of prospective randomized controlled trials, combining with the treatment recommendations of the National Comprehensive Cancer Network (NCCN) for USC in recent years, it is recommended that USC be treated by comprehensive staged surgery, combined with chemotherapy, radiotherapy, molecular targeted therapy and immunotherapy. At present, there is no consensus on the best treatment for uterine serous cancer. Now I will elaborate on the current status and progress of the treatment of uterine serous carcinoma related treatment, and hope to be helpful for clinical treatment.

Key words: Endometrial neoplasms, Surgical procedures, operative, Antineoplastic combined chemotherapy protocols, Radiotherapy, Immunotherapy