Abstract: Cervical diseases include cervical inflammation, cervical squamous intraepithelial lesions and cervical cancer. In recent years, it has been found that vaginal microflora, its cytokines and local immune system are related to the occurrence and development of cervical diseases. The vaginal micro-ecological environment of normal women is composed of a variety of microorganisms, of which lactobacillus play an important role in maintaining vaginal micro-ecological balance. The incidence rate of cervical cancer ranks first in female malignant tumors, and its occurrence is closely related to persistent infection of human papilloma virus. However, not all people infected with human papilloma virus develop into cervical cancer. Cervical cancer is caused by multiple factors. Vaginal diseases caused by changes in lactobacillus interact with human papilloma virus infection, and both participate in the occurrence and progression of cervical diseases. Systematic effective vaginal micro-ecological environment testing is very important for timely regulation of vaginal micro-ecological balance. The relationship between vaginal microflora and cervical diseases has become a research hotspot of many scholars. This article explores the occurrence and development of vaginal microecology and cervical diseases, and provides a theoretical basis for the prevention treatment and prognosis of cervical diseases, especially cervical cancer.

Key words: Vagina；, Uterine cervical diseases；, Papillomaviridae；, Lactobacillus