Journal of International Obstetrics and Gynecology ›› 2023, Vol. 50 ›› Issue (6): 623-626.doi: 10.12280/gjfckx.20230467

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Application of Ozone Therapy in Improving Vaginal Microecological Environment of Vaginitis

WAN Rui-xing, JIA Xue-ling, YUAN Yue, FU Xiao-ming, HU Jun-ping()   

  1. School of Nursing, Lanzhou University, Lanzhou 730030, China (WAN Rui-xing, FU Xiao-ming, HU Jun-ping); Reproductive Medicine Center, The First Hospital of Lanzhou University, Lanzhou 730000, China (JIA Xue-ling, YUAN Yue, HU Jun-ping)
  • Received:2023-06-21 Published:2023-12-15 Online:2023-12-13
  • Contact: HU Jun-ping E-mail:hjplandashengzhi@126.com

Abstract:

Ozone is a strong oxidizing gas, with bactericidal and anti-inflammatory effects, which has shown certain efficacy in the treatment of skin, joint and oral diseases. Vaginitis is a common gynecological disease with high clinical incidence and recurrence rate, and the clinical efficacy of drug treatment for vaginitis is unsatisfactory. The application of ozone therapy in the treatment process of vaginitis patients can kill vaginal pathogenic microorganisms by exerting the powerful oxidation effect of ozone and stimulating the generation of cytokines, accelerating the dissipation of inflammatory cells. It can also exert its nutritional properties of ozone, promoting the regeneration of vaginal mucosa cell and strengthen the local immunity of the vagina, restore the normal pH of the vagina, and rebuild the homeostasis of the vaginal environment. However, at present, there is no unified standard for the concentration, dosage, duration, follow-up period and selection of ozone properties in the treatment of vaginitis with ozone therapy. How to select the appropriate treatment plan according to the patient′s condition and play the best effect of ozone therapy will become the key to the promotion and application of ozone therapy in the future.

Key words: Ozone, Vaginitis, Microbiology, Dysbiosis, Lactobacillus