Relationship between Vaginal Epithelial Injury Repair and Microecological Environment

doi:10.12280/gjfckx.20240880

Abstract

Abstract:

Vaginitis is a common disease in obstetrics and gynecology, and its incidence is increasing year by year. The research of vaginal microecological environment has promoted clinical understanding of the pathogenesis of vaginitis and optimized the corresponding treatment protocols. However, at this stage, the treatment of vaginitis still faces the dilemma of unsatisfactory efficacy and high recurrence rate. With the in-depth research of the vaginal microecological environment, it is found that the development of vaginitis is closely related to vaginal epithelial cells, and microorganisms, their metabolites, and inflammatory reactions will directly or indirectly act on vaginal epithelial cells, which in turn affect the vaginal microecological environment. In recent years, scholars at home and abroad have proposed that vitamin D and estrogen have a positive effect on the repair of vaginal epithelial cells. Discussing the pathogenesis of vaginitis from the damage and repair of epithelial cells in the vaginal microenvironment may provide new ideas to improve the cure rate and reduce the recurrence rate of vaginitis.

Key words: Vaginitis, Inflammation, Vaginosis, bacterial, Vagina, Cellular microenvironment

CHEN Shu-lin, QIAO Qiao. Relationship between Vaginal Epithelial Injury Repair and Microecological Environment[J]. Journal of International Obstetrics and Gynecology, 2025, 52(1): 52-56.

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