Abstract: Superficial cervical vaginal myofibroblastoma is a rare and newly recognized benign tumor. The clinical data of 3 patients with superficial cervical vaginal myofibroblastoma treated in the Department of Obstetrics and Gynecology of the Second Hospital of Jilin University were reviewed retrospectively. Of the 3 patients, 2 were postmenopausal and clinically manifested as a vaginal mass. In general, the mass was round, with clear boundaries, and the size of the mass was about 3.0-4.0 cm. Under the microscope, the tumor was composed of uniform spindle and stellate cells. The tumor cells in the peripheral area were relatively sparse and the tumor cells in the central area were relatively dense. Immunohistochemical staining showed: Vimentin (+), Desmin (+), CD34 (-), ER (+), PR (+), SMA (-), S-100 (-). Through the elaboration of such cases, it is suggested that superficial cervical vaginal myofibroblastoma mainly affects the vulva, vagina and cervical area, and is easily confused with fibrous epithelial polyps, solitary fibrous tumors, and vascular myofibroblastoma. The definite diagnosis needs to be combined with pathological morphology, immunohistochemistry and clinical data.

Key words: Superficial cervical vaginal myofibroblastoma;, Diagnosis;, Diagnosis, differential, Pathology;, Immunohistochemistry