Abstract:

Well-differentiated papillary mesothelioma is a rare disease, and it is often found accidentally during surgery for other diseases. Its etiology is unknown, and its cause may be related to endometriosis. However, due to its low incidence, gynecologists generally do not know enough about it, which is easy to cause missed or misdiagnosed. This paper reported a case of well-differentiated papillary mesothelioma. The patient was admitted to the hospital for laparoscopic surgery for uterine fibroids. Intraoperative exploration revealed scattered patchy milky white corn-like lesions of 0.2-0.5 cm in diameter in the pelvic peritoneum and the posterior uterine wall serous membrane, with pelvic peritoneal endometriosis lesions next to them. Intraoperative biopsy of the lesion was performed, and well-differentiated papillary mesothelioma was diagnosed by histological pathology, immunohistochemistry and molecular detection. The pathogenesis, clinical manifestations, diagnosis, differential diagnosis and treatment of this disease were reviewed through the literature, and the diagnosis and treatment experience of this case was summarized.

Key words: Mesothelioma, Peritoneum, Endometriosis, Diagnosis,differential, Case reports