Advances in the Application of Nanomedicine in the Treatment of Endometriosis

doi:10.12280/gjfckx.20251123

Abstract

Abstract:

Endometriosis (EMs) is a common benign gynecological disease. Currently, the main treatment methods include drug therapy and surgical treatment, but both have certain limitations. Even after EMs surgery, long-term drug management is still required to prevent recurrence. Therefore, it is particularly important to explore new, effective, and well-tolerated drug treatment modalities. In recent years, drug delivery using nanotechnology has become a new approach for disease treatment. Nanomedicine has advantages such as targeting, improving pharmacokinetics, prolonging circulation time, increasing the bioavailability of poorly soluble drugs, and multi-mode integration, and has been successfully applied in the treatment of various tumor diseases. EMs also exhibits biological behaviors similar to those of tumor cells, so the strategies of applying nanomedicine in tumor treatment can be used in the treatment of EMs. Currently, the applications of nanomedicine in the treatment of EMs include antioxidant and anti-inflammatory therapies, pain treatment, immunotherapy, photothermal therapy, gene therapy, and multi-mode diagnosis and treatment. This review summarizes the relevant research on the application of nanomedicine in the treatment of EMs, providing new directions for clinicians in treating EMs.

Key words: Nanoparticles, Endometriosis, Drug delivery systems, Drug therapy, Therapy

WU Pei-yang, LU Jun, LAN Xi, LIANG Yan-chun. Advances in the Application of Nanomedicine in the Treatment of Endometriosis[J]. Journal of International Obstetrics and Gynecology, 2026, 53(1): 60-64.

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