Abstract: Clinical found gynecological malignant tumor patients often appear different degree of psychological barriers, including depression which is one of the common negative emotions in gynecologic malignant tumor patients. Different levels of depression and other negative emotions have certain adverse impact on the immunity, chemical treatment and quality of life in patients with malignant tumor, which can further affect their therapeutic effect and prognosis. Psychological intervention, antidepressant drug and other antidepressive treatment in patients with gynecological malignant tumor has irreplaceable position in the process of comprehensive treatment. We review the research progress of antidepressant treatment applied in the gynecology malignant tumor, and mainly focuses on the influence of depression in patients with gynecological tumors and the main antidepressant treatment.

Key words: Depression, Genital neoplasms, female, Therapy