Journal of International Obstetrics and Gynecology

Journal of International Obstetrics and Gynecology ›› 2012, Vol. 39 ›› Issue (5): 533-534.

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Experimental Study of Mefordcare Phytic Acid Ketone Effect on HeLa Cells Using MTT Assay

WU Zhi-dan，YANG Zhi-mou，YUE Tian-fu   

  1. College of Pharmacy，Nankai University，Tianjin 300071，China（WU Zhi-dan）；College of LifeSciences，Nankai University，Tianjin 300071，China（YANG Zhi-mou）；Tianjin Medical University General Hospital，Tianjin 300052，China（YUE Tian-fu）
  • Received:1900-01-01 Revised:1900-01-01 Published:2012-10-15 Online:2012-10-15

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Abstract: Objective：To study the ability of the No.1 and No.2 of type Ⅱ of Mefordcare Phytic Acid Ketone on
inhibiting the proliferation of HeLa cells which were cultivated in vitro，and provide the evidence for futher experiment. Methods：The HeLa cells which were cultivated in vitro was treated by eight different concentrations for 24，48 and 72h，MTT assay was employed to examine the growth suppression of HeLa cells. Results：Contrast with the control group，the apoptosis of the cells treated with these two numbers of the drug was increased and the growth rate was decreased. And the inhibition of HeLa cells in partly is in a concentration-dependent and time-dependent manner. Conclusions：The No.1 and No.2 of type Ⅱ of Mefordcare Phytic Acid Ketone could significantly inhibit the proliferation of HeLa cells.

Key words: HeLa cells, Uterine cervical neoplasms, Papillomaviridae, Phytic acid ketone, Methyl thiazolyl tetrazolium