Abstract: Objective：To explore diagnosis and treatment of acute appendicitis during pregnancy. Methods：retrospective analysis of the clinical data of 66 cases of acute appendicitis during pregnancy，29 patients didn't agree with surgery，so received conservative treatment，and 12 cases of uncontrolled infection，change to surgical treatment，37 cases were admitted to the hospital emergency surgical treatment. Results：66 patients discharge smoothly；eight patients after discharge required abortion in obstetrics and gynecology；2 patients had the abortion，one patient was premature birth at 10 days after surgery；no serious complications such as fetal distress，stillbirth and pregnant women death. Conclusions：Important means for the safety of maternal and infant is that timely diagnosis and surgical treatment of acute appendicitis during pregnancy. If symptoms of light infection，unapparent local peritonitis，and patients don't agree with surgery，we first do conservative treatment，and closely observe. If the treatment effect is not obvious，we then immediately surgery.

Key words: Appendicitis, Pregnancy, Ultrasonography, Diagnosis, Therapy