Abstract: Multiple sclerosis is a autoimmune demyelinating disease that affects the central nervous system，more commonly seen in women than in men，especially childbearing-age women. Multiple sclerosis itself does not increase complication of pregnancy. Although some studies have found that pregnant women with multiple sclerosis have increased incidences of their induced labor，the use of obstetric forcep and delivered low birth weight children，short stature children，the studies show no increase in congenital malformations and fetal mortality. Pregnancy，epidural anesthesia and breast-feeding do not increase the incidence，relapse rate and disease progression of multiple sclerosis. In this paper，the relationship between pregnancy and multiple sclerosis were reviewed，including interaction of multiple sclerosis and pregnancy and drug treatment during pregnancy and so on.

Key words: Multiple sclerosis, Pregnancy, Recurrence, Therapy