Abstract: Angiogenesis plays an important role in the pathogenesis of endometriosis. Based on this observation，many substances capable of inhibiting blood vessel formation have been tested to treat the disease during the last decade. These include growth factor inhibitors，endogenous angiogenesis inhibitors，statins，cyclo-oxygenase-2 inhibitors，immunomodulators，dopamine agonists and peroxisome proliferator-activated receptor agonists. This review will summarize recent anti-angiogenic researches of endometriosis and discuss the potential role of anti-angiogenic substances in the treatment of endometriosis.

Key words: Endometriosis, Vascular endothelial growth factor A, Angiogenesis inhibitors, Cyclooxygenase 2 inhibitors, Dopamine agonists, Peroxisome proliferator-activated receptors