Abstract: Research progress of the etiological and therapeutic mechanisms of endometriosis (EMs) are still not very clear. Well established animal model which created an appropriate method of evaluation is crucial to study the etiology and experiment treatment effect of EMs. In recent years, building simple non-invasive models with fluorescent transfection method has become a new direction to establish EMs model. Considering internationally on this method with its gradual progress of establishment in vitro and in vivo, selecting transfection process, fluorescent materials and color, quantitative and dynamic observation and measurement instrument in these years, it will be useful for the summary on these aspects of the work in the EMs animal models.

Key words: Endometriosis, Models, animal, Fluorescent dyes, Transfection