Journal of International Obstetrics and Gynecology ›› 2009, Vol. 36 ›› Issue (6): 440-442.

• 综述 • Previous Articles     Next Articles

MicroRNA and Cervical Cancer

ZHANG Jia-rong;LI Shuang-di;WAN Xiao-ping   

  1. The First People’s Hospital Affiliated Shanghai Jiaotong University, Shanghai 200080, China(ZHANG Jia-rong, LI Shuang-di);Shanghai International Peace Maternity and Child Health Hospital, Shanghai 200030, China(WAN Xiao-ping)
  • Received:1900-01-01 Revised:1900-01-01 Published:2009-12-15 Online:2009-12-15

Abstract: Cervical cancer is one of the most common malignant tumors,which is caused primarily by high risk human papilloma virus infection. MicroRNAs are endogenous noncoding small RNAs, which take part in many processes including virus infection and tumorigenesis. Great concern has been raised regarding cancer-related microRNAs recently. In cervical cancer, several microRNAs(miR-21, -143, -146a, -199a, et al) have been found to be de-expressed. Here we discuss the role of microRNAs in the development and progression of cervical cancer.

Key words: MicroRNA, Cervical cancer, Human papilloma virus, Tumor