Abstract: Objective：To study the feasibility and safety of the local excision of uterine adenomyoma. Methods：To retrospective analyze 107 women with symptomatic uterine adenomyoma in Nanjing Medical University Affiliated Suzhou Hospital from October 2005 to March 2012，who refused to receive hysterectomy. All of them received the local excision of uterine adenomyoma，100 of them received the operation with routine abdominal small incision，and 7 received the operation with laparoscopy. Comparative analyze the operative time，intraoperative amount of bleeding，postoperative dysmenorrhea，menstrual quantity and uterine adenomyoma recurrence. Results：In 6 months follow-up，the dysmenorrhea symptom of 79 women were all disappeared completely，the menorrhagia symptom of 43 women were all disppeared. 48 months follow-up of 28 cases，the dysmenorrhea of 2 women（7.1%） were relieved ＜50% took oral painkiller；60 months follow-up of 14 cases，the dysmenorrhea of 2 women（14.3%） were relieved ＜50%. 1 case took oral painkiller，1 case was given Mirena IUD；dysmenorrhea degree of 2 women（14.3%） were the same level，60 months after the local excision，both of them got hysterectomy. In 7 infertility women，1 woman got pregnant 3 years after the operation andterm birth，the other 3 women who already had child，got pregnant two months to 1 year after the operation，all of them received drug abortion, the other 3 infertility women were still infertile. Conclusions：By analyzing the follow-up data，the majority women with symptomatic uterine adenomyoma could achieve the complete relief of dysmenorrhea and menorrhagia through the local excision of uterine adenomyoma. The local excision of uterine adenomyoma can gradually replace hysterectomy for uterine adenomyoma，and it is worth clinical application.

Key words: Endometriosis, Laparoscopes, Hysterectomy, Dysmenorrhea, Menorrhagia, Follow-up studies