Journal of International Obstetrics and Gynecology ›› 2016, Vol. 43 ›› Issue (3): 279-281.

• 综述 • Previous Articles     Next Articles

Animal Research on the Relationship between Mothers′ Exposure to High Fat Diet and Offspring′s Metabolic Syndrome in the Adulthood

SU Li-jun,HUA Shao-fang   

  1. The Second Hospital of Tianjin Medical University,Tianjin 300211,China
  • Received:1900-01-01 Revised:1900-01-01 Published:2016-06-22 Online:2016-06-22
  • Contact: HUA Shao-fang

Abstract: Metabolic syndrome (MS) is a group of metabolic disorders of unknown etiology, obesity, insulin resistance (IR), dyslipidemia and hypertension form its core components. MS is related to the incidence of cardiovascular diseases and it may increase the risk of cardiovascular diseases. There is a certain correlation between mothers′ exposure to high fat diet and offspring′s MS in the adulthood. Early exposure to high-fat diet could increase the incidence of obesity, IR, dyslipidemia and hypertension in the adulthood, which is high risk factor of MS. Various changes in the environment of progestation, gestation and lactation of mothers will influence the metabolic status of offspring, and can affect the health of offspring for a long time in the adulthood. It′s time to pay attention to mothers′ health care before conception and during pregnancy particularly in order to reduce the occurrence of MS. The progress of animal research about the relationship is reviewed.

Key words: Pregnancy, Pregnant women, Metabolic syndrome X, Dietary fats, Pregnancy, Pregnant women, Metabolic syndrome X, Dietary fats