Abstract: Objective：To analyze the influence of different psychological intervention on anxiety, depression and pregnancy outcomes in different degrees of gestational diabetes mellitus (GDM) women and their families. Methods：300 GDM women and their families (their husband or mother) who accepted regular inspection and delivered at Shanghai First Maternity and Infant Hospital from April 2013 to November 2014 were randomly divided into a collective intervention group, a face to face psychological intervention group and a control group according to the intervention mode. Psychological intervention during pregnancy were six times, the GDM patients in each group were divided into GDM A1 (who were treated with diet therapy and exercise therapy) and GDM A2 (who need insulin therapy), compared the SAS, SDS scores and pregnancy outcome of GDM A1 and GDM A2 and their family members in each group before intervention (a week after the initial diagnosis of GDM), after intervention (36 weeks of pregnancy, 48 hours postpartum. 42 days postpartum). Results：The SAS and SDS scores of GDM women and their families in three groups were no significant difference before intervention (all P＞0.05). After psychological intervention, the SAS and SDS scores of GDM A1 and GDM A2 patients and their families in the collective intervention group and the face to face psychological intervention group were less than the scores of before intervention (both P＜0.01), meanwhile the SAS and SDS scores in the collective intervention group and the face to face psychological intervention group were less than that in control group (P＜0.01), and the SAS and SDS scores in collective intervention group were less than face to face psychological intervention group, the difference was significant (both P＜0.01). There was no significant difference in the pregnancy outcome of the three groups (P＞0.05). But, the incidence of maternal complications and the rate of caesarean section in the intervention group had the trend of lower. Conclusions：Psychological intervention can effectively improve GDM women and their families the symptoms of anxiety and depression, and the collective intervention was more conductive to the improvement of the symptoms of anxiety and depression of GDM patients and their families, it is worth in clinical promotion.

Key words: Diabetes, gestational, Pregnant women, Anxiety, Depression, Collective intervention, Family members, Diabetes, gestational, Pregnant women, Anxiety, Depression, Collective intervention, Face to face intervention, Family members