Abstract: Uterine sarcoma is a rare uterine malignant tumor with a high grade of malignancy and pool prognosis，which is easy to have local recurrence and distant metastasis. Surgery as the main treatment，emphasizes the standardization and individuation. Postoperative radiation treatment does not improve both disease-free survival rate and overall survival rate of uterine leiomyosarcomas patients. Adjuvant chemotherapy can improve overall survival rate of carcinosarcomas patients，therefore it is considered as the standard of therapeutic regimen. Trabectedin has demonstrated effective and reasonably safe for patients with advanced uterine leiomyosarcomas. The medical target therapy of uterine sarcoma is still at the exploratory stage.

Key words: Uterus, Leiomyosarcoma, Sarcoma, endometrial stromal, Carcinosarcoma, Gynecologic surgical procedures