Abstract: Objective：To compare the effects and safety of LigaSure vessel sealing system and bipolar electric coagulation in gynecological laparoscopic surgery. Methods：Analyzed retrospectively 180 cases of gynecologic laparoscopic surgery patients（salpingectomy，oophorectomy，hysterectomy）. In 90 cases，LigaSure vessel sealing system was applied to occlude the ovarian and uterine vessels. In another 90 cases，bipolar electric coagulation was used. The operation time，intra-operative blood loss，recovery condition after the operation and post-operative early complications were compared. Results：In both group， recovery condition after the operation and postoperative early complications were similar. There were significant differences between two methods in the postoperative morbidity. Conclusions：LigaSure vessel sealing system is safer than bipolar coagulation in effective vascular closure，reducing the amount of bleeding and shorten the operation time，reduce postoperative morbidity.

Key words: LigaSure vessel sealing system, Electrocoagulation, Laparoscopes, Gynecologic surgical procedures