Progress of Fluorescence Image-Guided Surgery in Gynecological Malignant Tumors

doi:10.12280/gjfckx.20230638

Abstract

Abstract:

Fluorescence image-guided surgery(FIGS) is a new technology in modern surgical practice, which uses near-infrared fluorescence(NIR) imaging agent to mediate the development of target tissue during surgery as a real-time, non-invasive and high-resolution diagnostic method to provide screen images for surgeons to achieve real-time intraoperative navigation. In gynecological malignant tumors, FIGS can be used to detect sentinel lymph nodes, perform lymphography, indicate tumor boundaries, detect tissue contamination and develop important blood vessels during surgery to evaluate blood supply. Due to the lack of targeting of NIR dye itself, targeted molecular probes combined with fluorescent dyes are being widely developed and used in clinical trials of gynecological malignant tumors. However, the high false positive rate is still the main problem hindering its clinical application. With the continuous development of new fluorescent dyes and imaging systems, FIGS may change the diagnosis and treatment strategy of gynecological malignant tumors and provide new treatment options for surgeons.

Key words: Spectroscopy, near-infrared, Fluorescent dyes, Optical imaging, Genital neoplasms, female, Diagnostic imaging, Gynecologic surgical procedures, Margins of excision

JIA Yan-feng, DANG Yun. Progress of Fluorescence Image-Guided Surgery in Gynecological Malignant Tumors[J]. Journal of International Obstetrics and Gynecology, 2024, 51(1): 47-51.

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