Abstract:

Peutz-Jeghers syndrome is an autosomal dominant genetic disease, often accompanied by a variety of gynecological tumors, and the tumor type is relatively rare, which is prone to misdiagnosis and missed diagnosis in clinical practice. We report a case of Peutz-Jeghers syndrome with ovarian sex cord tumor with annular tubules, ovarian mucinous tumor and cervical minimal deviation adenocarcinoma admitted to the First Affiliated Hospital of Dalian Medical University. The patient presented to the hospital for the first time with pelvic mass and was diagnosed as ovarian mucinous cystadenoma after ovarian tumor stripping. It was complicated with microscopic ovarian sex cord tumor with annular tubules, but the tumor recurred within a short time after the removal of the tumor twice, and eventually progressed to ovarian mucinous cystadenocarcinoma. The third operation was accidentally found to be accompanied by cervical minimal deviation adenocarcinoma. The clinical features, diagnosis and treatment process and postoperative follow-up of the patient are reviewed to improve clinicians′ cognition of gynecologic tumors associated with Peutz-Jeghers syndrome.

Key words: Peutz-Jeghers syndrome, Ovarian neoplasms, Uterine cervical neoplasms, Gynecologic surgical procedures, Case reports