Journal of International Obstetrics and Gynecology ›› 2022, Vol. 49 ›› Issue (1): 34-38.doi: 10.12280/gjfckx.20210298

• Research on Gynecological Malignancies:Review • Previous Articles     Next Articles

Progress in Diagnosis and Treatment of Vulvar Squamous Cell Carcinoma

QIN Zhao-juan, ZHENG Ai()   

  1. Department of Obstetrics and Gynecology, Key Laboratory of Birth Defects and Related Women and Children Diseases of the Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu 610041, China
  • Received:2021-03-31 Published:2022-02-15 Online:2022-03-02
  • Contact: ZHENG Ai E-mail:ZhengAi@163.com

Abstract:

The incidence of vulvar squamous cell carcinoma (VSCC) increases every year. Although the diagnosis and treatment of tumors are improving, the recurrence rate and death rate of late VSCC have not decreased obviously. Due to the rarity of VSCC, there are no randomized clinical trials to compare the advantages and disadvantages of different treatments. Traditional treatments mainly include surgery and radiotherapy, and the changing trend of the surgical methods tends to be more conservative surgical scope to achieve greater therapeutic effect for diseases. The application of laparoscopic inguinal lymph node dissection and sentinel lymph node biopsy is also gradually widespread, and immunotherapy is also on the rise. The purpose of this paper is to review the latest research progress in the diagnosis, surgical treatment, radiotherapy and chemotherapy of VSCC, to provide reference for follow-up clinical diagnosis and treatment.

Key words: Vulvar neoplasms, Carcinoma,squamous cell, Papillomaviridae, Gynecologic surgical procedures, Chemoradiotherapy,adjuvant, Sentinel lymph node, Sentinel lymph node biopsy, Prognosis