Abstract: With the development of molecular techniques, the research about the role of microRNA （miRNA） in tumor occurrence and development have became the new hot spot in bioscience field. MiR-183 gene cluster （miR-183 family） is a highly conservative gene cluster，which includes miR-183，miR-182 and miR-96，that located in 7 chromosome. Researches have shown that abnormal expression of miR-183 gene cluster can be found in variety of cancinomas. Based on the newest report at domestic and oversea, we review some recent literatures about the function of miR-183 family and the correlation between the miR-183 family and cancer.

Key words: MicroRNAs, Genital neoplasms, female, Neoplasms, Ovarian neoplasms, Uterine cervical neoplasms