国际妇产科学杂志

国际妇产科学杂志 ›› 2010, Vol. 37 ›› Issue (1): 9-11.

• 综述 • 上一篇    下一篇

缩宫素对神经精神系统发育的影响

陆廷凤, 于红   

  1. 210009 南京，东南大学临床医学院（陆廷凤），东南大学附属中大医院妇产科（于红）
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2010-02-15 发布日期:2010-02-15
  • 通讯作者: 于红

Influence of Oxytocin on the Development of Neuropsychiatric

LU Ting-feng, YU Hong   

  1. The Clinical Medical College of Southeast University，Nanjing 210009，China（LU Ting-feng）；Department of Gynecology and Obstetrics， Zhong Da Hospital Affiliated to the Southeast University，Nanjing 210009，China（YU Hong）
  • Received:1900-01-01 Revised:1900-01-01 Published:2010-02-15 Online:2010-02-15
  • Contact: YU Hong

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摘要： 缩宫素（oxytocin， OT）在分娩和泌乳中起重要作用，近年OT对神经精神系统发育的影响逐渐受到重视。分娩时主要来源于母体下丘脑的OT通过减少神经元活动及代谢的能量需求，对分娩过程中的胎脑起保护作用。OT同时作为神经递质或神经调质，调节儿童神经精神系统发育，并可能与儿童孤独症、成人社会行为、社会认知障碍相关。研究OT对神经精神系统发育的影响有重要意义。

关键词: 缩宫素, 神经精神系统, 发育

Abstract: Oxytocin is an important endocrine hormone for parturition and milk ejection. Recently influence of OT
on the neuropsychiatric system development has been gradually taken seriously. During delivery， the oxytocin mainly derived
from maternal hypothalamus， reducing neuronal activity and metabolic demand， thus helping to protect fetal neurons from
hypoxic insults. Oxytocin also regulates the development of neuropsychiatric system as a neurotransmitter or neuromodulator，
and has an association with children autism， adult social behavior and adult social cognition dysfunction. Thus， the
research of oxytocin’s effect on neuropsychiatric system development has important significance.

Key words: Oxytocin, Neuropsychiatric system, Development