国际妇产科学杂志

国际妇产科学杂志 ›› 2010, Vol. 37 ›› Issue (3): 198-200.

• 综述 • 上一篇    下一篇

代谢综合征与子宫内膜癌

倪镌,寿华锋,俞华   

  1. 310022 杭州，浙江省肿瘤医院
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2010-06-15 发布日期:2010-06-15

Metablic Syndrome and Endometrial Cancer

NI Juan， SHOU Hua-feng，YU Hua   

  1. Department of Gynecology Oncology， Zhejiang Cancer Hospital，Hangzhou 310022，China
  • Received:1900-01-01 Revised:1900-01-01 Published:2010-06-15 Online:2010-06-15

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摘要： 代谢综合征（MS）是多种代谢物异常集结的病理状态，与其有关的远期不良结局日益受到关注。MS已成为乳腺癌、直肠癌等恶性肿瘤发病的高危因素。MS疾病发生发展的各环节与子宫内膜癌发病机制关系密切，且存在共同的细胞因子表达异常。MS亦可能是子宫内膜癌发病的危险信号，由此，其可能成为早期筛查子宫内膜癌的新途径，对其综合治疗可能成为防治子宫内膜癌及增加疗效的有效方法。

关键词: 代谢综合征, 子宫内膜癌, 细胞因子

Abstract: Metabolic syndrome（MS） is a pathological condition of abnormal aggregation of multiple metabolite resulting. The long-term adverse outcomes were payed more and more attention by people. MS had been high risk factors of breast cancer and carcinoma of rectum. MS was marginally associated with an increased risk of endometrial cancer. Abnormal expression with cytokines was found both on MS and endometrial cancer. Therefore， MS may be a new point to screen， prevention and cure endometrial cancer.

Key words: Metabolic syndrome, Endometrial carcinoma, Cytokines