国际妇产科学杂志 ›› 2010, Vol. 37 ›› Issue (4): 277-280.

• 综述 • 上一篇    下一篇

上皮性卵巢癌的治疗进展

李 蕊,令狐华   

  1. 400016 重庆医科大学附属第一医院妇产科
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2010-08-15 发布日期:2010-08-15

Treatment Progress in Epithelial Ovarian Cancer

LI Rui, LINGHU Hua   

  1. Department of Obstetrics and Gynecology, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China
  • Received:1900-01-01 Revised:1900-01-01 Published:2010-08-15 Online:2010-08-15

摘要: 上皮性卵巢癌(EOC)是常见的妇科恶性肿瘤之一,早期不易发现,病死率高。其治疗主要是以手术、化疗为主的综合治疗。处理的第一步应该是准确诊断,全面分期,以及对转移病灶实施满意的细胞减灭术,但应充分重视术前评估。紫杉醇加卡铂是晚期EOC的标准一线化疗方案。肠梗阻是主要的终末期并发症,应重视其姑息治疗。卵巢癌复发、耐药仍然需要研发新的治疗途径。

关键词: 卵巢肿瘤, 抗肿瘤联合化疗方案, 姑息治疗, 治疗

Abstract: Epithelial ovarian cancer is one of the most common female reproductive malignancies. It holds high mortality because most patients are diagnosed at advanced stages. Patients are primarily managed with surgery and chemotherapy. With careful pre-operative evaluation for the existence and resectability of metastatic diseases, the first step of management should be accurate diagnosis, thorough staging, with optimal surgical cytoreduction of metastatic diseases. At present, paclitaxel plus carboplatin become the first-line chemotherapeutic regimen of advanced EOC. Palliative treatment is needed for bowel obstruction(a major end-of-life complication) . Howerver, new strategies for recurrent and resistant patients needs further developing.

Key words: Ovarian neoplasms, Antineoplastic combined chemotherapy protocols, Palliative care, Therapy