国际妇产科学杂志

国际妇产科学杂志 ›› 2011, Vol. 38 ›› Issue (6): 487-489.

• 综述 • 上一篇    下一篇

盆腔炎动物模型建立及应用进展

柴 昕,王建六   

  1. 100044 北京大学人民医院妇产科(柴昕现在北京积水潭医院妇产科工作)
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2011-12-15 发布日期:2011-12-15
  • 通讯作者: 王建六

Establishment and Clinical Application of Animal Model in Pelvic Inflammatory Disease

CHAI Xin，WANG Jian-liu   

  1. Department of Obstetrics and Gynecology，Peking University People′s Hospital，Beijing 100044，China（CHAI Xin now working at Department of Obstetrics and Gynecology of Beijing Ji Shui Tan Hospital）
  • Received:1900-01-01 Revised:1900-01-01 Published:2011-12-15 Online:2011-12-15
  • Contact: WANG Jian-liu

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被引次数

17

摘要： 盆腔炎性疾病（PID）是困扰广大生育期女性的多发病。建立一个适宜的动物模型，对于了解PID的临床发病机制、药物的评价监测以及疫苗开发利用都起着极为重要的作用。目前盆腔炎动物模型建模方法较多，建立的模型在应用方面有一定局限性，尚需进一步研究完善。综述PID动物模型的建立及其应用情况。

关键词: 盆腔炎性疾病, 疾病模型, 动物, 衣原体科感染, 奈瑟球菌, 淋病, 支原体属

Abstract: Pelvic inflammatory disease （PID）is a serious and costly　common disease for reproductive women. Studying an appropriate animal model will be useful for ascertaining its pathogenesis, selection and evaluation of anti-inflammatory medicines，and potential vaccine candidates. Until now, there are many methods for the PID animal models. However，the models have some limitations. It is needed further study afterwards. This article focuses on the establishiment and application of animal model in PID.

Key words: Pelvic inflammatory disease, Disease models, animal, Chlamydiaceae infections, Neisseria gonorrhoeae, Mycoplasma