国际妇产科学杂志

国际妇产科学杂志 ›› 2013, Vol. 40 ›› Issue (2): 171-173.

• 论著 • 上一篇    下一篇

妊娠期急性脂肪肝及其临床诊疗分析

王 静 , 李增彦   

  1. 300052 天津医科大学总医院妇产科
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2013-04-15 发布日期:2013-04-15
  • 通讯作者: 李增彦

Clinical Diagnosis Analysis of Acute Fatty Liver

WANG Jing，LI Zeng-yan   

  1. Department of Obstetrics and Gynecology，Tianjin Medical University General Hospital，Tianjin 300052，China
  • Received:1900-01-01 Revised:1900-01-01 Published:2013-04-15 Online:2013-04-15
  • Contact: LI Zeng-yan

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摘要： 目的：探讨妊娠期急性脂肪肝（AFLP）的发病特点、诊疗方案、并发症及转归，以提高母婴存活率。方法：回顾性分析近7年在我院确诊为AFLP的14例患者的分娩方式、诊疗经过及预后。结果：14例AFLP患者1例死亡，8例产后出血，2例多脏器功能衰竭，新生儿轻度窒息1例，重度窒息2例，死胎1例。结论：AFLP早期诊断、及早终止妊娠及各科室的相互配合是十分必要的。应严密监测及调节凝血功能、肝肾功能，防止AFLP患者产后出血及多脏器功能衰竭，提高母婴存活率。

关键词: 脂肪肝, 产后出血, 诊断, 治疗

Abstract: Objective：To explore the characteristics，approach to patient care，complications and outcome of acute fatty liver of pregnancy in order to increase the survival probability of maternal and infant. Methods: Retrospectively analyze the 14 patients who were diagnosed as AFLP during the last 7 years in our hospital and their diagnosis and treatment and prognosis. Results: 1 patient died of acute fatty liver of pregnancy，8 postpartum hemorrhage and 2 MODS，1 case of neonatal mild choking， 2 cases of severe suffocation，1 case of death in the womb. Conclusions: It is necessary to early diagnosis，termination of pregnancy and the cooperation among the different offices for acute fatty liver of pregnancy. There is high possibility for AFLP patients to occur postpartum hemorrhage and MODS，it should be monitored strictly，adjusted coagulation function and liver and kidney function to avoid postpartum hemorrhage and MODS，and increase the livability of maternal and infant.

Key words: Fatty liver, Postpartum hemorrhage, Diagnosis, THERAPY