国际妇产科学杂志 ›› 2020, Vol. 47 ›› Issue (5): 531-535.

• 妇科肿瘤研究 综述 • 上一篇    下一篇

子宫肉瘤辅助治疗

冯淑杰,周启敏,何玲玲,李睿彦,俞晓雲,王海琳   

  1. 730000  兰州大学第一临床医学院(冯淑杰,何玲玲,李睿彦,俞晓雲,王海琳);甘肃省人民医院(周启敏,王海琳)
  • 收稿日期:2020-05-06 修回日期:2020-07-14 出版日期:2020-10-15 发布日期:2020-10-27
  • 通讯作者: 王海琳,E-mail:hailinwang2020@163.com E-mail:hailinwang2020@163.com

Adjuvant Therapy of Uterine Sarcoma 

FENG Shu-jie,ZHOU Qi-min,HE Ling-ling,LI Rui-yan,YU Xiao-yun,WANG Hai-lin   

  1. The First Clinical Medical College of Lanzhou University,Lanzhou 730000,China(FENG Shu-jie,HE Ling-ling,LI Rui-yan,YU Xiao-yun,WANG Hai-lin);Gansu Provincial Hospital,Lanzhou 730000,China(ZHOU Qi-min,WANG Hai-lin)
  • Received:2020-05-06 Revised:2020-07-14 Published:2020-10-15 Online:2020-10-27
  • Contact: WANG Hai-lin,E-mail:hailinwang2020@163.com E-mail:hailinwang2020@163.com

摘要: 子宫肉瘤(uterine sarcoma)是一种发病罕见、恶性程度高的疾病,占所有子宫体恶性肿瘤的3%~7%。该病发病隐匿,组织学类型多样,至今仍未建立标准治疗方案。目前首选治疗方式为手术治疗,但术后复发率依然居高不下,严重影响患者远期生存率。因此子宫肉瘤的术后辅助治疗已成为国内外研究焦点之一,但对其可靠性及有效性目前仍无定论。本文总结了常见类型子宫肉瘤术后辅助治疗的研究现状及进展,特别是对子宫平滑肌肉瘤和低级别子宫内膜间质肉瘤术后辅助治疗方法进行罗列与分析,以期为临床提供相应治疗思路。

关键词: 子宫肿瘤;, 肉瘤;, 平滑肌肉瘤;, 肉瘤, 子宫内膜间质;, 抗肿瘤联合化疗方案;, 子宫肉瘤

Abstract: Uterine sarcoma is a rare but aggressive tumor accounting for 3%-7% of all uterine cancers. The disease is insidious and diverse histologically, and no standard treatment has been established. At present, surgical treatment is the preferred treatment, but postoperative recurrence rate is still high,which seriously affects the long-term survival of patients. Therefore, the postoperative adjuvant treatment of uterine sarcoma has become one of the focus of research at home and abroad, but its reliability and effectiveness still have no unified conclusion. In this review, we have summarized current states and latest progress of postoperative adjuvant therapy in common types of uterine sarcoma, especially focusing on the methods of postoperative adjuvant treatment of uterine leiomyosarcoma and low-grade endometrial stromal sarcoma, in order to provide the corresponding treatment ideas for the clinical practice.

Key words: Uterine neoplasms;, Sarcoma;, Leiomyosarcoma;, Sarcoma, endometrial stromal;, Antineoplastic combined chemotherapy protocols;, Uterine sarcoma