关键词: 宫颈肿瘤, 化学疗法, 辅助, 抗肿瘤联合化疗方案, 放射疗法

Abstract: Cervical cancer is the fourth leading cause of cancer deaths in women worldwide，5-year survival of some patients with stage ⅠB or more is only about 50%，the main reasons for treatment failure is uncontrol local tumor or distant metastasis. The surgery and radiotherapy are still traditional treatment pattern for patients withⅠB-ⅡB stage. The reasonable treatment play an important role in reducing the recurrence of cervical cancer. In the past 20 years，the comprehensive therapy and individualized therapy as the main treatment for cervical cancer，and achieved some results，but there are still controversial. Various treatments have been used, including neoadjuvant chemotherapy, postoperative adjuvant chemotherapy, concurrent chemotherapy and radiotherapy, three dimensional conformal intensity modulated radiation therapy, three dimensional intracavitary brachytherapy, lymph node sampling, sentinel lymph node biopsy, nerve-sparing radical hysterectomy. Recently, the best treatment mode of cervical cancer ⅠB-ⅡB are still controversial. Surgery, radiotherapy and(or) chemotherapy are applied reasonably and effectively in improving of prognosis and increasing survival rate of cervical cancer ⅠB-ⅡB, but there are many complications at the same time. In this paper，the status of the treatment of cervical cancer ⅠB-ⅡB mode period，including chemotherapy，surgery，radiotherapy and combined therapy were reviewed.

Key words: Uterine cervical neoplasms, Chemotherapy, adjuvant, Antineoplastic combined chemotherapy protocols, Radiotherapy