Journal of International Obstetrics and Gynecology ›› 2021, Vol. 48 ›› Issue (3): 259-263.doi: 10.12280/gjfckx.20200724

• Obstetric Physiology & Obstetric Disease Review • Previous Articles     Next Articles

Research Progress of Compound Pregnancy after In Vitro Fertilization and Embryo Transfer

SHEN Wei-chen, LU Xiao-sheng, LYU Jie-qiang()   

  1. Reproductive Center, The Second Affiliated Hospital of Wenzhou University, Wenzhou 325000, Zhejiang Province, China
  • Received:2020-08-04 Published:2021-06-15 Online:2021-06-25
  • Contact: LYU Jie-qiang E-mail:jieqianglv@sohu.com

Abstract:

Compound pregnancy (heterotopic pregnancy, HP) is an extremely dangerous ectopic pregnancy. The incidence of HP in natural conception is not high, but in recent years, the popularization of in vitro fertilization and embryo transfer (IVF- ET) and ovulation induction techniques, the incidence of HP has increased compared with the previous period. Patients with HP usually only have non-specific symptoms such as abdominal pain and vaginal bleeding in the early stage. Due to the existence of intrauterine gestation sac, their ectopic gestational sac is especially easy to be misdiagnosed and missed, which can easily lead to the continued development of the patient′s ectopic gestational sac and can cause serious life-threatening consequences such as hemorrhage in the abdominal cavity or even shock. Therefore, a full understanding of the related risk factors of HP, corresponding measures to prevent the occurrence of HP before ET or ovulation induction technology. Early diagnosis after HP and effective treatment after diagnosis will improve the prognosis of patients and it seems particularly important. This review summarizes the progress in diagnosis and management of HP after IVF-ET.

Key words: Pregnancy,heterotopic, Fertilization in vitro, Embryo transfer, Pregnancy,ectopic, Ultrasonography, Therapy