Research Progress of Diagnostic Markers for Endometriosis

doi:10.12280/gjfckx.20201115

Abstract

Abstract:

Endometriosis (EMs) is a benign disease with high malignant potential in women of childbearing age, with a incidence rate of 10%. Because the onset of the disease is hidden, and can only be diagnosed by laparoscopy and histopathology and other invasive operations, the lack of sensitive and specific biological indicators in clinical diagnosis leads to the delay of diagnosis and treatment of the disease, which seriously affects the quality of life of women. Therefore, it is of great significance to find non-invasive biomarkers for clinical diagnosis and treatment of EMs. Studies have found that there are some diagnostic markers in the serum, urine and menstrual blood of women with EMs. The use of these markers has the advantages of simple, rapid and noninvasive diagnosis, which has become an important direction in the diagnosis of the disease.

Key words: Endometriosis, Biomarkers, Diagnosis, Histones, Zinc finger E-box-binding homeobox 1, Matrix metalloproteinase 2, Matrix metalloproteinase 9, Galectins, HMGB1 protein

SUN Xiu-li, ZHANG Guang-mei. Research Progress of Diagnostic Markers for Endometriosis[J]. Journal of International Obstetrics and Gynecology, 2021, 48(5): 579-582.

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