Journal of International Obstetrics and Gynecology ›› 2021, Vol. 48 ›› Issue (5): 588-591.doi: 10.12280/gjfckx.20201206

• Gynecological Disease & Related Research: Review • Previous Articles     Next Articles

Progress in Diagnosis and Treatment of Septate Uterus

GAO Li, XIA En-lan()   

  1. Department of Obstetrics and Gynecology, The First Hospital of Lanzhou University, Lanzhou 730000, China (GAO Li); Hysteroscopic Center, Fuxing Hospital, Capital Medical University, Beijing 100038, China (XIA En-lan)
  • Received:2020-12-21 Published:2021-10-15 Online:2021-10-27
  • Contact: XIA En-lan E-mail:xiaenlan@126.com

Abstract:

Septate uterus is the most common type of congenital uterine malformation, which may lead to adverse pregnancy outcomes such as abortion, premature delivery and fetal growth restriction. At present, the etiology of septate uterus is not clear. The researchers try to explore the causes of septate uterus and the mechanism of adverse pregnancy outcome through the study of gene level, embryonic development process and anatomical structure of septate uterus, but they can not completely reveal the causes of its formation. Septate uterus can be diagnosed by ultrasound. With the development of diagnostic techniques, magnetic resonance imaging (MRI) and three-dimensional ultrasound technology make the diagnosis of septate uterus more accurate, but hysteroscopic diagnosis is still the gold standard for the diagnosis of septate uterus. Because the current classification system for uterine deformities is different and the definition of septate uterus is different, it often leads to different therapeutic outcomes. Although there are a large number of retrospective studies and prospective controlled studies supporting the treatment of septate uterus by transcervical resection of septum (TCRS), high-quality randomized controlled studies are needed to support clinical decisions.

Key words: Septate uterus, Uterus, Etiology, Diagnosis, Therapy