Abstract:

Cervical squamous intraepithelial lesion (SIL) is closely related to the occurrence of cervical cancer. In recent years, the incidence of cervical SIL is gradually increasing and showing a younger trend. Cervical conization is widely used as the first choice for the treatment of cervical high-grade squamous intraepithelial(HSIL) patients. For patients with fertility requirements after conization, most existing studies believe that cervical conization does not affect their fertility, but may increase the incidence of adverse pregnancy outcomes such as preterm delivery, abortion, premature rupture of membranes and perinatal death, and will not significantly affect the progress of labor or increase the rate of cesarean section. The pregnancy outcome after LEEP is better than that of CKC, and contraception should be given at least 6 months after conization. The increase of depth and volume of conization can increase the incidence of adverse pregnancy outcome, and prophylactic cervical ligation is not necessary after conization. For patients with fertility requirements, we should pay attention to postoperative follow-up, individually guide pregnancy according to intraoperative and postoperative recovery, closely monitor cervical length and vaginal infection during pregnancy, and actively encourage patients without vaginal delivery contraindications to carry out vaginal trial delivery.

Key words: Uterine cervical diseases, Conization, Fertility, Pregnancy outcome, Therapy