Abstract:

The pathogenesis of HELLP syndrome and reversible posterior leukoencephalopathy syndrome (RPLS) is still unclear, lack of unified guidance in clinical treatment. A case of prenatal HELLP syndrome complicated with RPLS was reported. The main clinical manifestations of the patients were headache and blindness, the blood pressure was elevated. Laboratory examination showed that lactate dehydrogenase, alanine aminotransferase and aspartate aminotransferase increased, and platelets decreased. Patient has chills, convulsions irritability and other delirium symptoms after emergency lower segment cesarean section, was given rescue treatment such as analgesia, sedation, antihypertensive, diuresis, anti-infection, liver protection and multidisciplinary consultation. After 10 days, the patient′s condition was stable, with normal vision and stable blood pressure control. For patients with hypertensive disorders during pregnancy, those with symptoms of neurological and visual disturbances should consider the possibility of RPLS, and diagnose and treat as soon as possible to ensure maternal and infant safety.

Key words: HELLP syndrome, Posterior leukoencephalopathy syndrome, Vision disorders, Pregnancy outcome, Therapy, Prognosis