Advances in the Anatomical and Histological Characteristics of the Human Uterosacral Ligament and Related Biomechanical Studies

doi:10.12280/gjfckx.20230290

Abstract

Abstract:

Pelvic organ prolapse (POP) is a disease caused by weakened pelvic support structures mediated by mutiple factors. The primary risk factors are multiple pregnancies and vaginal deliveries. However, the pathophysiological process of POP is not yet known. Surgery is one of the most important methods of treating moderate to severe POP. Surgical procedures associated with the uterosacral ligament (USL) play an important role in restoring apical support and have a high surgical success rate. However, the risk of postoperative recurrence and complications are still present, largely due to a lack of adequate knowledge of the USL anatomy histology and biomechanics. Accurate knowledge of the anatomical location and tissue composition of the USL not only allows finding the most suitable site for USL suspension, but also prevents intraoperative damage to adjacent organs and tissues, such as the ureter, rectum, nerves and blood vessels. In addition, a comprehensive understanding of the biomechanical properties of the various components of USL can also suggest new solutions for the study of POP pathogenesis, prevention strategies and customization of personalized surgery.

Key words: Uterus, Ligaments, Pelvic organ prolapse, Anatomy, Histology, Biomechanical phenomena

XUE Feng-qin, ZHAO Shu-rui, ZHAO Ye. Advances in the Anatomical and Histological Characteristics of the Human Uterosacral Ligament and Related Biomechanical Studies[J]. Journal of International Obstetrics and Gynecology, 2023, 50(6): 606-612.

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