Journal of International Obstetrics and Gynecology ›› 2023, Vol. 50 ›› Issue (3): 332-336.doi: 10.12280/gjfckx.20221059

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Progress in Treatment of Infertility Associated with Cesarean Scar Defect

WANG Zhuo-min, HU Qian-yu, SUN Tao, XU Jian()   

  1. Center for Reproductive Medicine, The Fourth Affiliated Hospital Zhejiang University School of Medicine, Yiwu 322000, Zhejiang Province, China
  • Received:2022-12-15 Published:2023-06-15 Online:2023-06-27
  • Contact: XU Jian, E-mail: xuj@zju.edu.cn

Abstract:

Cesarean scar defect (CSD) is one of the common complications after cesarean section. The clinical manifestations include abnormal uterine bleeding, pelvic pain and secondary infertility. With the evolution of fertility policy and the increase of cesarean section rate, the infertility associated with it is gradually gaining attention. There is no consensus on the treatment options of infertility secondary to CSD currently. In patients combined with small amounts of uterine cavity effusion, the prolonged GnRHa down-regulation protocol can be used to assist reproduction. While in patients with abnormal uterine bleeding or obvious endometrial cavity fluid, surgery should be considered as first-line treatment. However, there is still a lack of uniformity in the choice of surgical approach and surgical plans are usually determined based on the residual myometrial thickness on the scar. In addition, treatment options such as intrauterine ozone infusion, traditional Chinese medicine conditioning and physiotherapy, and stem cell transplantation may also have potential benefits in the treatment of secondary infertility in CSD.

Key words: Uterus, Cicatrix, Diverticulum, Cesarean section, Infertility, female, Reproductive techniques, assisted, Surgical procedures, operative