Research Progress of Oxytocin in Preventing Postpartum Hemorrhage

doi:10.12280/gjfckx.20240247

Abstract

Abstract:

Postpartum hemorrhage is a common obstetric complication and the leading cause of maternal death worldwide, and weak uterine contraction is the main cause of postpartum hemorrhage. Uterine contractions such as oxytocin and carbe oxytocin are the first-line drugs for the prevention and treatment of weak uterine contraction. Oxytocin, as the first-line uterine contractions recommended by WHO for the prevention of postpartum hemorrhage, has not yet reached a consensus on the medication route, administration time, dosage and rate in different delivery methods. Among them, the use of oxytocin in high-risk groups of postpartum hemorrhage such as multiple pregnancies and obesity is different from that in low-risk groups. Current research focuses on how to achieve the best preventive effect with the lowest dose and reduce the adverse effects of the drugs in high-risk groups of postpartum hemorrhage. This paper reviews the prevention of postpartum hemorrhage with oxytocin and its administration plan. The application of oxytocin in different delivery modes was summarized and the future research direction was prospected.

Key words: Oxytocin, Postpartum hemorrhage, Natural childbirth, Cesarean section, Prevention

YANG Ke-xin, ZHANG Yan. Research Progress of Oxytocin in Preventing Postpartum Hemorrhage[J]. Journal of International Obstetrics and Gynecology, 2024, 51(4): 463-467.

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