Journal of International Obstetrics and Gynecology ›› 2024, Vol. 51 ›› Issue (4): 458-462.doi: 10.12280/gjfckx.20240136

• Obstetric Physiology & Obstetric Disease: Review • Previous Articles     Next Articles

Research Progress on the Brain Injury in Survivors Following Single Intrauterine Fetal Death in Monochorionic Twins

HE Yu-ru, XIA Ge-qing()   

  1. Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, China
  • Received:2024-02-04 Published:2024-08-15 Online:2024-07-25
  • Contact: XIA Ge-qing, E-mail: xgq1967@vip.sina.com

Abstract:

With the development of ovulation promotion and assisted reproductive technology, the rate of multiple pregnancies is increasing year by year. Single intrauterine fetal death(sIUFD) in twins is a serious complication of monochorionic twins in middle and late stages. After single intrauterine death, neurological impairment of the surviving fetus is an important factor affecting the long-term prognosis of newborns and infants, which seriously affects the quality of the population. The study of the mechanisms of neurological damage and effective monitoring of possible brain damage in surviving fetus are essential for the prevention of severe brain injury complications and important basis for causing the management of pregnancy and the timing of delivery. By identifying the risk factors associated with neurological damage in surviving fetuses with sIUFD, adopting appropriate monitoring and intrauterine treatment, and developing appropriate delivery plans, we can reduce the incidence of poor neurological outcomes in surviving fetuses.

Key words: Pregnancy, twin, Diseases in twins, Neurodevelopmental disorders, Brain injuries, Fetofetal transfusion, Magnetic resonance imaging, Monochorionic twins, Single intrauterine fetal death