Abstract: Metabolomics is a new “omics” techniques which uses analytical chemistry detection methods and bioinformatics strategy to study the global metabolites in biological systems （cells， tissues， living organisms）. Any physiological or pathological changes can be revealed by the metabolic phenotype， the metabolic changes demonstrated in the development of ovarian cancer must be measured by metabolomics. The systematic，holistic，dynamic information for ovarian cancer will be obtained， which can provide a theoretical basis for early diagnosis and proper treatment. There is a review for the concept of metabolomics， their research methods and applications on ovarian cancer.

Key words: Metabolism, Ovarian neoplasms, Magnetic resonance spectroscopy, Gas chromatography-mass spectrometry, Biomedical research