Abstract: Preeclampsia（PE） is an idiopathic hypertension syndrome that occur after 20th week of gestation，whose etiology and pathogenesis have not yet been completely elucidated. MicroRNA（miRNA） is a class of endogenous single-stranded small non-coding RNA. Recent studies verified abnormal expression of miRNAs in placenta of preeclampsia and screening of maternal serum miRNAs expression spectrum helped early prediction of PE. Further investigation of PE-related miRNAs and their target genes would contribute to demonstration of PE pathogenesis，then provide new ways for the prevention and treatment of PE. This review summarized recent advances in PE-related miRNAs.

Key words: Pre-eclampsia, MicroRNAs, Placenta, Genes, Serology