Abstract: Adenomyosis(AM) is a common gynecological disease, in recent years, the incidence is rising. Studies on adenomyosis and infertility-related mechanisms has become a hot topic. Although there is no sufficient epidemiological data to prove that there is a genuine relationship between AM and infertility. However, with improved image and therapeutic levels in AM , indirect evidence shows AM with low fertility. There is no specific mechanism for the interpretation of adenomyosis cause of infertility, this article will combine basic pathological anatomy pathophysiology, and endometrial receptivity abnormalities, endocrine abnormalities and other aspects related to adenomyosis′s research progress, to discuss the relationship between AM and infertility factors.