Abstract: Vulvar and vaginal atrophy is a common symptom in postmenopausal women, the most prevalent symptoms are vaginal dryness, dyspareunia, vaginal irritation or itching, can disturb patients′ life and work. More and more patients need therapy in order to obtain a higher quality of life. According to the NAMS′s guidelines, the most common treatment of vulvar and vaginal atrophyis local hormone therapy in recent years. This method is first-line treatment. But some patients have difficulty to accept hormone therapy, or have contraindication of hormone treatment. Therefore, vaginal moisturizer, selective estrogen receptor modulator, prasterone, laser, traditional Chinese medicine and other treatment methods are derived. This paper will review the different treatment methods and mechanism and its application in patients, in order to provide reference for the treatment of vulvovaginal atrophy.

Key words: Postmenopause；, Vulva；, Vagina；, Atrophy；, Therapy；, Quality of life