Vulvar Solitary Fibrous Tumor: A Case Report and Literature Review

doi:10.12280/gjfckx.20230482

Abstract

Abstract:

Solitary fibrous tumor (SFT) is a rare mesenchymal tumor, and vulvar SFT is particularly rare. Patients with vulvar SFT usually present with a painless mass in the vulva, the pathogenesis and etiology of which are unknown. Due to the extremely low incidence, gynecologists generally have insufficient understanding of it, which is easy to cause missed diagnoses and misdiagnoses. The data of a 33-year-old case of primary vulvar SFT were reported. The patient was admitted to the hospital due to self-conscious vulvar discomfort for 1 year, and color Doppler ultrasound showed a solid subcutaneous mass in the right labia majora. High-energy ultra pulse carbon dioxide laser vulvar mass resection was performed, and the mass appeared oval during the operation, with a size of about 3.0 cm×2.5 cm, with clear boundaries to surrounding tissues, and did not involve the muscular layer. It was diagnosed as vulvar SFT (low malignant potential) by pathology, immunohistochemistry and Demicco model risk stratification, and close follow-up was recommended. After 6 months of postoperative follow-up, no tumor recurrence or metastasis was seen.

Key words: Solitary fibrous tumors, Vulvar neoplasms, Carbon dioxide, Lasers, gas, Immunohistochemistry, Diagnosis

ZHOU Chang, DUAN Hua, GUO Yin-shu, HE Chun-yan. Vulvar Solitary Fibrous Tumor: A Case Report and Literature Review[J]. Journal of International Obstetrics and Gynecology, 2023, 50(6): 660-664.

Figures/Tables 5

References 23

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病例	作者	年龄（岁）	症状	肿瘤位置	治疗方案	肿瘤最大径（cm）	核分裂象/ 10 HPF	组织坏死	免疫组织化学	随访时间（个月）	随访结局
1	Biedrzycki等^[8]（2007）	45	无	右侧外阴	完整切除	6	无	少量	CD34、Bcl-2、Vimentin、CD99	9	未复发
2	陈文静等^[9]（2009）	62	疼痛	右侧外阴	完整切除	6	无	无	CD34、Bcl-2、Vimentin、CD99	16	未复发
3	He等^[10]（2010）	39	无	左侧外阴	完整切除	10	<1	无	CD34、CD99、Vimentin	10	未复发
4	Vaysse等^[11]（2011）	37	无	左侧外阴	完整切除	5.5	<1	无	CD34、Bcl-2	16	未复发
5	Taki等^[12]（2012）	56	无	右侧外阴	完整切除	5	<1	无	CD34	18	未复发
6	Nag等^[13]（2015）	57	无	左侧外阴	完整切除	10	<1	无	CD34、Bcl-2	24	未复发
7	刘丹等^[14]（2018）	53	无	左侧外阴	完整切除	3.5	<1	无	CD34、CD99、Vimentin、Bcl-2、STAT6	8~30	未复发
8	刘丹等^[14]（2018）	65	无	左侧外阴	完整切除	4.5	<1	无	CD34、CD99、Vimentin、Bcl-2、STAT6	8~30	未复发
9	Tandon^[15]（2021）	47	无	左侧外阴	完整切除	4.5	2	无	CD34、Vimentin、STAT6	10	未复发

病例	作者	年龄（岁）	症状	肿瘤位置	治疗方案	肿瘤最大径（cm）	核分裂象/ 10 HPF	组织坏死	免疫组织化学	随访时间（个月）	随访结局
1	Biedrzycki等^[8]（2007）	45	无	右侧外阴	完整切除	6	无	少量	CD34、Bcl-2、Vimentin、CD99	9	未复发
2	陈文静等^[9]（2009）	62	疼痛	右侧外阴	完整切除	6	无	无	CD34、Bcl-2、Vimentin、CD99	16	未复发
3	He等^[10]（2010）	39	无	左侧外阴	完整切除	10	<1	无	CD34、CD99、Vimentin	10	未复发
4	Vaysse等^[11]（2011）	37	无	左侧外阴	完整切除	5.5	<1	无	CD34、Bcl-2	16	未复发
5	Taki等^[12]（2012）	56	无	右侧外阴	完整切除	5	<1	无	CD34	18	未复发
6	Nag等^[13]（2015）	57	无	左侧外阴	完整切除	10	<1	无	CD34、Bcl-2	24	未复发
7	刘丹等^[14]（2018）	53	无	左侧外阴	完整切除	3.5	<1	无	CD34、CD99、Vimentin、Bcl-2、STAT6	8~30	未复发
8	刘丹等^[14]（2018）	65	无	左侧外阴	完整切除	4.5	<1	无	CD34、CD99、Vimentin、Bcl-2、STAT6	8~30	未复发
9	Tandon^[15]（2021）	47	无	左侧外阴	完整切除	4.5	2	无	CD34、Vimentin、STAT6	10	未复发